The GhostBed mattresses are designed to support up to 350 lbs per side. To date, we have tested the GhostBed Classic, GhostBed Luxe, and GhostBed Flex.
For heavier sleepers, I would recommend the GhostBed Flex as it has a slightly firmer feel (6.5 out of 10) as well as a thicker profile.

The GhostBed website says 13″, although the version we tested was only 11.5″ thick. Regardless, extra thickness helps provide better support and pressure relief for heavier sleepers.

For a thicker profile in an all-foam configuration, the GhostBed Luxe is another 13″ option. The Luxe is a foam mattress whereas the Flex is a hybrid. Hybrid support systems generally provide better support to heavier sleepers.
The Luxe is also a touch softer than the Flex, which may not be suitable for heavier sleepers.